体外循环心脏术后胃肠道并发症的研究进展

Gastrointestinal complications following cardiac surgery with cardiopulmonary bypass

体外循环(cardiopulmonary bypass,CPB)心脏术后消化系统并发症在临床工作中很常见,包括麻痹性肠梗阻、应激性溃疡、缺血性肠炎、消化系出血、急性胆囊炎、急性胰腺炎、急性肝功能不全等.对这些并发症缺乏高灵敏性及特异性的诊查方法,早期诊断困难,导致患者病死率很高.所以如何正确识别这些并发症的高危因素,对早期诊断与及时治疗具有重要意义.本文着重探讨CPB术后胃肠道各种并发症的机制,危险因素,并对其相关诊疗策略目前的研究进展进行综述.

Gastrointestinal complications following cardiac surgery with cardiopulmonary bypass include paralytic ileus, stress ulcer, acute ischemic coli- tis, gastrointestinal bleeding, acute cholecystitis, acute pancreatitis, acute hepatic failure and so on. Due to the lack of diagnostic tests with high specificity and sensitivity, the early diagnosis of these complications is difficult, which leads to a higher mortality rate. Therefore, accurately identifying the risk factors is important for early diagnosis and treatment. The purpose of this paper is to review the pathogenesis, risk factors, diagnosis and treatment of gastrointestinal complications after cardiac surgery with cardiopulmonary bypass.