柴胡鳖甲汤治疗慢性肝炎临床疗效观察

Clinical Observation of Chronic Hepatitis Treatment with Bupleurum Turtle Decoction

目的:探讨柴胡鳖甲汤治疗慢性病毒性肝炎的临床疗效及安全性。方法:选取56例慢性病毒性肝炎患者,随机分为治疗组和对照组,两组均给予常规的护肝药物进行治疗,治疗组在此基础上加用柴胡鳖甲汤,1剂/d,分2次服用,早晚各1次,两组均连续治疗4周,观察临床疗效、主要生理指标变化及不良反应等。结果:两组患者经治疗后,临床症状缓解,生理指标改善,对照组总有效率为64.3%,治疗组总有效率为92.9%,治疗组总有效率明显高于对照组,具有显著性差异(P<0.05);两组均未出现严重的不良反应。结论:柴胡鳖甲汤用于治疗慢性病毒性肝炎,具有疗效较好、服用安全、经济实惠等特点,具有一定的临床借鉴意义。

Objective ： To investigate the clinical efficacy and safety of the treatment of chronic viral hepatitis with Bupleurum Turtle Decoction. Method： 56 cases of chronic hepatitis were randomly divided into treatment group and control group. Both groups were given routine drug treatment. The treatment group was treated with Bupleurum Turtle Decoction additionally, one dose a day, twice a day in the morning and evening. The two groups were treated for 4 consecutive weeks. The clinical, effects, the main physiological changes and adverse reactions were observed. Results ： After treatment, clinical symptoms and physiological indicators were improved. The control group＇s total effective rate was 64.3% and the total effective rate of treatment group was 92.9%. The treatment group had a significant difference （P〈0.05）. Two groups both had no serious adverse reactions. Conclusion ： Bupleurum Turtle Decoction for the treatment of chronic viral hepatitis has good effect, taking the advantages of safety, economical and other characteristics, and has certain clinical reference.