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认知功能损害与踝臂指数相关性研究 被引量:2

Clinical Study on Correlation of Ankle-Brachial Index with Cognitive Impairment
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摘要 目的:探讨踝臂指数(ABI)评价老年人认知功能损害的临床价值。方法:共选取86例住院患者纳入研究,对符合研究标准的患者进行ABI测量、病史采集及常规实验室指标检查,采用简易精神状态量表(MMSE)评估患者认知功能,主要观察MMSE与ABI、临床指标的相关性。结果:认知正常组1.01±0.24与认知损害组0.96±0.19之间ABI有显著性差异(P<0.05),MMSE与ABI存在相关性(P<0.05)。结论:认知功能损害的患者存在ABI降低,可能与动脉硬化引起靶器官损害有关。 Objective : This study aimed to examine the relationship between ankle-brachial index( ABI ) and cognitive impairment in elderly. Methods: We studied 86 in-patients who were referred to Dongzhimen Hospital. All the patients underwent ABI measurement,mini-mental state examination ( MMSE ),laboratory examination and history collection. The tin,relation between ABI and cognitive impairment were analysed. Results : There was significant difference between normal cognitive ( 1.01 ± 0.24 ) and cognitive impairment ( 0.96 ± 0.19 ). And MMSE was positively correlated with ABI ( P〈0.05 ). Conclusion : ABI can predict the cognitive impairment, which may be associated with target organ damages caused by atheroselerosis.
出处 《辽宁中医药大学学报》 CAS 2014年第6期75-77,共3页 Journal of Liaoning University of Traditional Chinese Medicine
基金 国家重大新药创制平台项目(2011ZX09302-006-01) 北京市科委项目(Z111107056811043) 教育部高等学校学科创新引智基地项目(B08006) 北京中医药大学创新团队项目(2011-CXTD-21) 2013年北京中医药大学自主选题资助项目(2013-JYBZZ-XS-131)
关键词 踝臂指数 认知功能 痴呆 ankle brachial index cognitive function dementia
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参考文献16

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