免疫抑制剂研究进展

Progress of immunosuppressant research

免疫抑制剂环孢素在临床上应用已超过 16年 ,但其使用仍有一定的局限性。近年来 ,可用于免疫抑制剂的新药数量成倍增长 ,如霉酚酸酯、他克莫司、西罗莫司、达克力莫和巴期力莫等。结合治疗药物浓度监测 ,本文就免疫抑制药物的研究进展作一综述。

Progress in immunosuppressant research was developed rapidly in recent years,and a number of new agents have been marketed since the first member,cyclosporin,came into market 16 years ago.In this paper,some new immunosupressants,such as mycophenolate mofetil,tacrolimus,sirolimus,daclizumab and basiliximab,were reviewed in conjunction with drug concentration monitoring.