冠心病患者血清中cTnI和hs-CRP水平变化及意义

Changes and Significance of Serum Levels of cTnI and hs-CRP in Patients with Coronary Heart Disease

目的:探讨冠心病患者血清中心肌肌钙蛋白O(cTnI)和超敏C反应蛋白(hs-CRP)水平变化及意义。方法:选取我院2009年5月至2013年4月收治的100例冠心病患者,将这些患者作为治疗组,另选取同期来我院进行健康体检的100例人员作为对照组,运用金标法检测两组人员的cTnI水平,运用胶体金法检测hs-CRP水平。结果:治疗组血清cTnI和和hs-CRP均明显比对照组高(P<0.01);治疗组患者cTnI和hs-CRP的阳性例数分别为56例和78例,阳性率分别为56%、78%,hsCRP的阳性率比cTnI高(P<0.05)。结论:冠心病患者血清中cTnI和hs-CRP水平显著升高,可以作为诊断冠心病的重要指标。

Objective：To investigate the changes and significance of serum troponin center （ cTnI） and high-sensitivity C-reactive protein （ hs-CRP ） levels of patients with coronary heart disease .Method：100 cases of coronary heart disease patients treated in our hospital from May 2009 to April 2013 were selected , they were regarded as the treatment group , and the other 100 cases of healthy people in the corresponding period in our hospital was selected as control group , The cTnI level was detected by gold standard method , and hs-CRP level was detected by colloidal gold method .Result：The serum cTnI and hs-CRP of the treat-ment group were significantly higher （ P 〈0.01） than those of the control group;cTnI and hs-CRP positive cases of patients in the treatment group were 56 cases and 78 cases, the positive rates were 56%and 78%, the positive rate of hs-CRP was higher than cTnI （P〈0.05）.Conclusion：The cTnI and hs-CRP levels of coronary artery disease patients are significantly elevated , they can be used as an important indicator in the diagnosis of coronary heart disease .