米索前列醇预防产后出血的临床治疗效果观察

Observation on the Clinical Effect of Misoprostol in the Prevention of Postpartum Hemorrhage

目的观察米索前列醇预防产后出血的临床效果。方法选取该院收治的足月分娩产妇182例,将其随机分为对照组和实验组,每组91例,对照组采用缩宫素肌注治疗,实验组采用米索前列醇口服治疗,观察比较两组患者的临床效果及反应情况。结果与对照组比较,实验组第三产程时间、产后出血量及产后出血症状的发生率明显较少,组间比较差异有统计学意义(P<0.05);而两组不良反应情况比较,差异无统计学意义(P>0.05)。结论米索前列醇预防产后出血的治疗效果优于缩宫素,且价格便宜,值得临床推广应用。

Objective To observe the clinical effect of misoprostol in the prevention of postpartum hemorrhage. Methods 182 cases of puerperants with term birth admitted in our hospital were randomly divided into the control group and the experimental group with 91 cases in each. The control group was treated with oxytocin intramuscularly, and the experimental group was given miso-prostol oral treatment. The clinical effect and adverse reactions of two groups of patients were observed and compared. Results Compared with the control group, the duration of the third stage of labor, postpartum hemorrhage volume, and the incidence of postpartum hemorrhage of the experimental group were significantly less than those of the control group, the differences were sta-tistically significant （P〈0.05）; but the difference in adverse reactions between two groups was not statistically significant （P〉0.05）. Conclusion For the prevention of postpartum hemorrhage, the effect of misoprostol is better than that of oxytocin, and the price is inexpensive, which is worthy of clinical application.