高频震荡治疗新生儿胎粪吸入综合征(MAS)合并呼吸衰竭的疗效观察

The clinical effect of High-frequency oscillation treatment of Neonatal Meconium qspiration syndrome with respiratory failure

目的:探讨并总结高频振荡对新生儿肽粪吸入综合征合并呼吸衰竭的临床疗效,进一步寻求更好的治疗措施。方法:选取儿科诊断为胎粪吸入综合征合并呼吸衰竭的新生儿70例,随机分为两组,每组35例。试验组采用高频振荡(HFO)辅助通气治疗呼吸衰竭,对照组采用常频通气(SIM)模式治疗。对比两组治疗前后血气改善情况、上机时间、并发症发生率及总有效率。结果:试验组上机时间(2.56±1.39)d、并发症的发生率8.75%、总有效率为77.19%,对照组上机时间(3.06±2.19)d、并发症的发生率为14.28%、总有效率为57.3%,两组的血气对比、上机时间、有效率及并发症的发生率之间比较,差异具有统计学意义(P<0.05)。结论:高频振荡治疗新生儿胎粪吸入综合征合并呼吸衰竭,值得临床推广。

Objective To study and summarize the clinical effect of the high frequency oscillation of neonatal peptide fecal inhalation syndrome combination of respiratory failure,further search of a better treatment measures. Method To choose pediatric diagnosis of meconium inhaled syndrome combination of respiratory failure ,70 cases of newborn, were randomly divided into two groups, each group of 35. The experimental group adopts the method of high frequency oscillation treatment, control group treated with conventional pattern of breathing machine. Compared the two groups after treatment in both groups after treatment in patients with blood oxygen saturation ,relieve symptoms, and patient satisfaction. Results The experimental group of computer time was （ 2.56 ± 1.39 ） d, The incidence of complications was 8. 75%, the total effective rate was 77.19%, the control group of computer time was （3.06 ±2. 19） d, The incidence of complications was 14.28%, the total effective fate was 57.3%, Blood gas, computer time, the total effective rate and the incidence of complications of two groups were compated, the difference was statistically significant （ P 〈 0.05 ）. Conclusion High frequency oscillation treatment neonatal meconium inhaled syndrome combination of respiratory failure, and is worth clinical promotion.