缺血修饰白蛋白在下肢深静脉血栓治疗中的应用探讨

The application of ischemia modified albumin in patients with venous thrombosis of lower limb

目的:探讨血清缺血修饰白蛋白浓度水平的检测在下肢深静脉血栓患者治疗中应用的意义。方法:选择26例存在不同程度下肢深静脉血栓患者,并排除有心源性疾病为治疗组。对照组为健康体检者10例,检测其血清缺血修饰白蛋白和D-二聚体在治疗前和治疗后浓度水平,并对结果进行统计分析。结果:血清缺血修饰白蛋白浓度水平在治疗前和治疗后比较差异具有统计学意义(P<0.05)。结论:下肢静脉血栓患者缺血修饰蛋白浓度水平增高,且缺血修饰白蛋白浓度水平与下肢深静脉血栓严重程度有关。

Objective To explore the clinical significance of isehemia modified albumin（IMA） in serum in patients with venous thrombosis of lower limb. Method 26 patients with venous thrombosis of lower limb in diffent levels and non - cardie disease were chosen as the treatment group. 10 healthy people as controls. The levels of IMA and D - dimer in serum before and after treatment were detected, results were statistically analyzed. Results The levels of IMA after treatment were significantly different, compared to the level before treatment（ P 〈 0. 05）. Conclusion The serum levels of IMA vises in patients with venous thrombosis of lower limb and is related to the severity of venous thrombosis of lower limb.