5186例阴道分泌物五联检检测结果的回顾性分析

Retrospective Survey on Detected Results of 5186 Vaginal Secretion Samples by Vaginitis Multitest Kit

目的检测本地区妇科门诊患者细菌性阴道病、念珠菌阴道炎、滴虫性阴道炎及阴道菌群失调症的发生率;分析细菌性阴道病、念珠菌阴道炎及滴虫性阴道炎与菌群失调的相关性,用以指导医生的临床治疗。方法采用阴道炎五联检试剂检测方法,对5186例阴道分泌物标本进行过氧化氢、白细胞酯酶、唾液酸苷酶、脯氨酸氨基肽酶、乙酰氨基葡萄糖苷酶及PH值的测定;分析细菌性阴道病、念珠菌阴道炎、滴虫性阴道炎、阴道菌群失调症的发生率及其与菌群失调的相关性。结果在5186例疑似阴道炎的妇科门诊患者中,阴道菌群失调症3559例,阳性检出率为68.6%;细菌性阴道病794例,阳性检出率为15.3%;念珠菌阴道炎477例,阳性检出率为9.2%;滴虫性阴道炎124例,阳性检出率为2.4%。在794例细菌性阴道病患者中,菌群失调检出率为100%;在477例念珠菌阴道炎患者中,菌群失调检出率为85.1%;在124例滴虫性阴道炎患者中,菌群失调检出率为91.9%。结论在本地区妇科阴道炎患者中,阴道菌群失调症最为常见,其次为细菌性阴道病和念珠菌阴道炎,滴虫性阴道炎最为少见;细菌性阴道病、念珠菌阴道炎及滴虫性阴道炎与阴道菌群失调均有很高的相关性。

Objective This retrospective survey was made to investigate and analyze the epidemic characteristics of bacterial vaginosis（BV）, candidal vaginitis（VC）, trichomonas vaginitis（TV） and dysbacteriosis in local gynecology outpatients and their correlations with dysbacteria, in order to guide clinic treatments. Methods The vaginitis multitest kit was performed on 5186 vaginitis suspects to detect hydrogen peroxide, leukocyte esterase, neuraminidase, proline aminopeptidase, N-aeetyl-D-glucosaminidase and pH value in vaginal secretion. The correlation between BV, VC, TV and dysbacteria was also analyzed. Results In all samples, positive rate of vagina dyshacteriosis was 68. 6%（3559/5186）, BV was 15.3%7（794/5186）, VC was 9.2%（477/5186）, and TV was 2.4%（124/5186）. Among patients with dysbacteria, the detection rate of BV, VC and TV were 100 %, 85.1% and 91.9%, respectively. Conclusion The results showed that among vaginitis patients in the region, vagina dysbacteriosis was common, BV and VC were secondary, TV is most rare. There were high correlation between BV, VC, TV with vagina dysbacteria.