进食对肝脏瞬时弹性检测仪检测肝脏硬度值的影响

Effect of meal on the accuracy of Fibrotouch assessment of liver stiffness measurement in hepatitis B patients and HBV correlated with cirrhosis patients

目的探讨进食对第三代肝脏瞬时弹性检测仪(Fibrotouch)检测慢性乙型肝炎肝硬化和慢性乙型肝炎患者肝脏硬度值的影响。方法应用Fibrotouch对46例乙肝肝硬化患者及40例慢性乙型肝炎患者检测早晨空腹和餐后0.5、1、2 h的肝脏弹性硬度值,分析空腹和餐后各时点肝脏硬度值的差异,并采用肝脏瞬时弹性成像仪(Fibroscan)同时进行复测和验证。结果应用Fibrotouch及Fibroscan检测,乙肝肝硬化患者空腹状态的肝脏硬度值分别与餐后0.5、1、2 h的肝脏硬度值比较,差异无统计学意义(P均﹥0.05);慢性乙型肝炎患者空腹肝脏硬度值分别与餐后0.5、1、2 h的肝脏硬度值比较,差异也无统计学意义(P均﹥0.05)。结论是否进食对于Fibrotouch检测乙肝患者肝脏硬度值的结果无明显影响。

Objective To investigate the effect of meal on the accuracy of Fibrotouch and Fibroscan assessment of liver stiffness measurement（LSM） in hepatitis B patients and in HBV correlated with cirrhosis patients. Methods Fibro-touch and Fibroscan were used to test LSM in 46 cirrhosis patients and 40 hepatitis B patients, respectively. LSM were performed before meal and 0.5, 1, 2 h after meal. The differences of LSM values before and after meal were compared and analyzed. Results The LSM of Fibrotouch and Fibroscan before and after meal were not significantly different （P﹥0.05） both in cirrhosis group and in hepatitis B group. Conclusion Meal has no effect on Fibrotouch and Fibroscan technique in the assessment of LSM in hepatitis B patients and cirrhosis patients. The measurement can be performed at any time.