中文版双相谱系诊断量表效度与信度研究(英文)

The Validity and Reliability of the Chinese Version ipolar Spectrum Diagnostic Scale(BSDS)

目的:探讨双相谱系诊断量表(Bipolar Spectrum Diagnostic Scale,BSDS)在中国的效度及信度。方法:在原作者授权下,根据量表翻译的原则,我们将英文版的BSDS翻译成中文并完成回译。按DSM-IV标准,连续入组的114例BD患者,双相I型(BD-I)61例、双相II型(BD-II)53例及37例单相抑郁(UD)患者,所有患者完成了中文版BSDS。87例患者(57.62%)在4周后重测。结果:BD组BSDS分(15.11±4.25)显著高于UD组(11.89±3.81)。BD-I组BSDS分(15.44±4.94)与BD-II组BSDS分之间无显著差异,但均显著高于UD组。BSDS总分重测信度为0.83(P<0.01)。主成分分析显示以前四因子解释BSDS的结构效度最佳(特征根值分别为2.35,2.31,2.21及1.80,对总体变量贡献度为48.24%)。BSDS的内部一致性(Cronbach’s alpha)是0.75。ROC曲线分析显示BSDS可区分BD组与UD组,曲线下面积为0.70,13分为最佳划界分(敏感性0.74、特异性0.54)。中文版BSDS可区分BD-II组与UD组,但无法区分BD-I组与BD-II组(P=0.39)。结论:本研究显示中文版BSDS对中国的心境障碍患者的效度及信度达到心理测量学的标准,可以在中国临床环境中使用。

Objective The aim of this study was to investigate the validity and reliability of the Chinese version of Bipo-lar Spectrum Diagnostic Scale（C-BSDS）. Methods： We have translated the English version BSDS into Chinese version withthe agreement of the author of the scale. 114 consecutive patients with BD（61 patients with bipolar I disorder, 53 patientswith bipolar II disorder） and 37 patients with UD in outpatients and inpatients departments diagnostically interviewed withDSM-IV were rated by C-BSDS. The test-retest reliability with interval of four weeks was investigated in 87 patients（57.62%）. Results： A four-factor solution was preferred by the factors analysis. The Eigenvalues of the four factors were2.35, 2.31, 2.21 and 1.80 respectively. The four factors together accounted for 48.24% of the total variance. The internalconsistency （Cronbach＇ s alpha） of the C-BSDS was 0.75. The test-retest reliability of the C-BSDS was 0.83（P〈0.01）. A C-BSDS screening score of 13 or more was the optimal cutoff between the patients with BD and UD（sensitivity 0.74, specificity0.54） by ROC curve analysis. C-BSDS could effectively differentiate BD-II patients with UD patients, but not with BD-I patients. Conclusion： The study demonstrated good psychometric properties of the C-BSDS, suggesting that the C-BSDS isan effective instrument to screen bipolar spectrum disorder in Chinese population.