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CXCR4与CXCR6在宫颈上皮内瘤变和宫颈癌中的表达及临床意义 被引量:3

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摘要 目的:探讨趋化因子受体4(CXC chemokine receptor 4,CXCR4)和趋化因子受体6(CXC chemokine receptor 6,CXCR6)在宫颈上皮内瘤变及宫颈癌中的表达及意义。方法 :采用RT-PCR和免疫组化检测CXCR4及CXCR6的表达,分析其与患者的临床病理参数及预后的相关性。结果:CXCR4和CXCR6在宫颈高级别上皮内瘤变组织、宫颈癌组织和转移淋巴结中高表达。CXCR4、CXCR6与宫颈癌患者的临床分期、淋巴结转移相关。结论:CXCR4和CXCR6可能参与宫颈癌的发生发展。
出处 《实用医学杂志》 CAS 北大核心 2014年第12期1924-1926,共3页 The Journal of Practical Medicine
基金 东莞市医疗卫生类科技计划项目(编号:201210515000601)
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同被引文献32

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