急性冠脉综合征患者N端B型脑钠肽浓度测定的临床意义

Clinical significance of N-terminal B-type natriuretic peptide precursor determination in patients with acute coronary syndrome

目的探讨急性冠脉综合征（ACS）患者血浆N端B型脑钠肽前体（NT—proBNP）水平的价值。方法选取本院2011年12月～2013年12月收治的60例ACS患者，并与同期50名在本院做冠脉造影正常者进行比较。结果ACS患者的NT—proBNP水平高于正常组，且急性心肌梗死高于不稳定性心绞痛，多支病变高于单支病变（P〈0．05）。结论NT-proBNP水平可作为评价心肌缺血范围和严重程度的指标。

Objective To explore the value of N-terminal B-type natriuretic peptide precursor （NT-proBNP） in patients with acute coronary syndrome （ACS）. Methods 60 cases of patients with ACS in our hospital from December 2011 to December 2013 were selected and compared with 50 cases of patients whose coronary angiography were normal in our hospital. Results The level of NT-proBNP in patients with ACS were higher than that of the normal group,patients with acute myocardial infarction was higher than that of patients with unstable angina,and multivessel disease was higher than that of single branch lesion （P〈0.05）. Conclusion Level of NT-proBNP can be used as the index of the range and the severity of myocardial isehemia.