长春西汀治疗椎基底动脉供血不足的临床分析

Clinical analysis of vinpocetine treating vertebrobasilar insufficiency

目的评价长春西汀治疗椎基底动脉供血不足（VBI）的临床效果。方法选取201P年3月～2013年12月本院收治的VBI患者87例，随机分为观察组（n=44）和对照组（n=43〉，观察组采用长春西汀治疗，对照组采用盐酸地芬尼多治疗。1周后比较两组患者的临床疗效、椎动脉与基底动脉的平均血流速度。结果观察组中优25例（56．8％），良13例（29．5％），差6例（13．6％），对照组中优15例（34．9％），良12例（27．9％），差16例（37．2％），两组的临床疗效比较差异有统计学意义（P〈0．05）；观察组的左椎动脉平均血流速度为（36．9±7．3）cm／s，右椎动脉为（39．1±6．3）ends，基底动脉为（40．1±4．9）cm／s，对照组的左椎动脉平均血流速度为（30．3±5．7）ends，右椎动脉为（29．5±613）ctrds，基底动脉为（33．8±7．0）cm／s．两组的椎动脉与基底动脉的平均血流速度比较差异有统计学意义（P〈0．05）。结论长春西汀治疗VBI的临床效果好，能明显增加椎基底动脉血流，值得临床予以推广。

Objective To evaluate the clinical effect of vinpocetine treating vertebrobasilar insufficient （VBI）. Methods 87 patients with VBI treated in our hospital from March 2011 to December 2013 were selected and randomly divided into the observation group （n=44）and the control group （n=43）.The observation group was treated with vinpocetine,while the control group was treated with hydrochloric acid difenidol.After one week,the clinical efficacy,average blood flow velocity of vertebral artery and basilar artery in the two groups were compared. Results In the observation group,25 cases （56.8%） were excellent,13 cases （29.5%） were good and 6 cases （13.6%） were bad,while in the control group they were 15 cases （34.9%）,12 （27.9%） and 16 （37.2%）respectively,and there was a statistical difference of clinical effect of the two grouos （P〈0.05）.In the observation group,the left average blood flow velocity was （36.9±7.3） cm/s,the right average blood flow velocity was （39.1±6.3） cm/s,the average blood flow velocity of basilar artery was （40.1±4.9） cm/s,while they were （30.3±5.7） cm/s,（29.5±6.3） cm/s,（33.8±7.0） cm/s respectively and there was a statistical difference of average blood flow velocity of vertebral artery and basilar artery in the two groups （P〈0.05）. Conclusion The clinical effect of vinpocetine treating VBI is good,it can significantly increase the blood flow of vertebrobasilar artery.It is worthy of clinical promotion.