摘要
目的比较宫腔镜手术与刮宫术治疗子宫内膜息肉（EP）型不孕症患者激素表达水平及预后的影响。方法选取本院2010年1月～2013年3月不孕门诊诊治EP型不孕症患者85例为观察组，随机分为宫腔镜亚组45例、刮宫亚组40例。分别予宫腔镜手术与刮宫术治疗，并对患者进行1年的随访；另选择同期因男性因素或输卵管因素不孕就诊、并经阴道B型超声及官腔镜检查除外EP和其他内膜病变的已婚妇女43例为对照组。观察和比较3组的激素表达水平及预后情况。结果3组的雌二醇（E2）、雌激素受体（ER）、孕激素受体（PR）表达水平比较差异无统计学意义（19〉0．05）；宫腔镜亚组的1年内妊娠率（77．78％）明显高于刮宫亚组（40．00％）（P〈0．05）；宫腔镜亚组的EP复发率（6．67％）低于刮宫亚组（15．00％）（P〈0．05）。结论官腔镜手术治疗EP相对于刮宫术，其日后受孕率高，复发率低。
Objective To compare the influence of hysteroscopic operation and curettage on hormone expression level and prognosis in patients with infertility and endometrial polyp （EP）. Methods 85 cases of patients with infertility and endometrial polyp treated in infertility outatient department of the hospital from January 2010 to March 2013 were selected as observation group,then randomly divided into hysteroscopy subgroup（45 cases） and curettage subgroup（40 cases）, they were treated with hysteroscopic operation and curettage respectively,and 1-year follow-up was carried out.At the same period,43 married women who were infertility due to male factor or fallopian tube factor were selected as control group,they all excluded EP and other endometrial diseases via transvaginal B type ultrasound examination and hysteroscopic examination.Hormone expression level and prognosis was observed and compared respectively among the three groups. Results The expression of estradiot（E 2）,estrogen receptor（ER）,progesterone receptor（PR）in three groups had no significant difference（P〉0.05）.l-year pregnancy rate in hysteroscopy subgroup（77.78%）was significantly higher than that in curettage subgroup（40.00%,P〈0.05）.Recurrence rate in hysteroscopy subgroup（6.67%）was lower than that in curettage subgroup （15.00%,P〈0.05）. Conclusion Compared with curettage operation,hysteroscopy operation has higher future pregnancy rate and lower recurrence rate in the treatment of EP.
出处
《中国当代医药》
2014年第17期37-40,共4页
China Modern Medicine
关键词
息肉
子宫内膜
手术
宫腔镜
刮宫
激素
妊娠
Polyp
Endometrial
Operation
Hysteroscopy
Uterine curettage
Hormone
Pregnancy
