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DPP-4抑制剂潜在的抗动脉粥样硬化作用研究进展 被引量:1

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摘要 心血管疾病是糖尿病最主要的致死率。药物治疗能够降低高血糖,也能够降低糖尿病相关的心血管疾病。DPP-4抑制剂被研制用作降血糖的治疗药物。在这类药物当中,尤其是维格列汀和西格列汀,能够降低进食后的餐后血糖、通过增加前臂血流量来改善内皮功能、还具有抗炎效应,DPP-4抑制剂还能通过降低颈动脉内膜中层的厚度采降低临床症状不明显的动脉粥样硬化,然而能否降低动脉粥样硬化,其最终结果将会由临床实验来验证。
作者 张星星 郝菲
出处 《药物与人》 2014年第6期43-44,共2页 Medicine & People
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