不同年龄段体质量超标患者的心脏变时性分析

Chronotropic Response in Overweight Patients of Different Ages

目的：探讨不同年龄段体质量超标患者在平板运动试验中心脏变时性的差异。方法：选取2013年1月-2013年5月在复旦大学附属中山医院行平板运动试验的632例患者，根据体质量指数（body mass index，BMI）分为对照组（BMI〈25kg／m^2，n=382）及体质量超标组（BMI≥25kg／m^2，n=250）；每组根据年龄再分为3组：青年组（≤44岁），中年组（45～59岁），老年组（≥60岁）。行平板运动试验后，比较不同年龄段体质量超标患者与正常体质量患者心脏变时性的差异。结果：中年体质量超标组运动后最大峰值心率降低、心脏变时功能不良指标降低，与中年对照组相比差异有统计学意义（P〈0．05）；老年体质量超标组运动峰值最大代谢当量降低、心脏变时功能不良指标降低，与老年对照组相比差异有统计学意义（P〈0．05）。结论：中老年体质量超标患者心脏变时功能异常，且随着年龄的增加加剧。

Objective：To explore the difference in heart ehronotropic response during treadmill exercise test in overweight patients of different ages. Methods： From January 2013 to May 2013, 632 patients were selected and divided according to body mass index （BMI） into control group （BMI〈25 kg/m2 , 382 cases） and overweight group （BMI≥25 kg/m2 , 250 cases）. Both groups were divided into 3 subgroups according to age, including youth group （age≤44）, middle-aged group （age 45-59） and old-aged group （age≥60）. Subjects among different age groups underwent treadmill exercise test, and the ehronotropic responses were compared. Results： The maximum peak heart rate and the indicators for chronotropic response in middle-aged group with overweight reduced significantly compared to those in the control group （P〈0.05）. The maximum metabolic equivalent of energy and the indicators for chronotropic response in the old-aged group with overweight reduced significantly compared to those in the control group （P〈0.05）. Conclusions： Chronotropic response is abnormal in middle- and old-aged patients with overweight. With the increase of age, the difference increases more significantly.