河源地区血清降钙素原和C反应蛋白在重症肺炎患者诊变化过程中的价值

目的：为了更好的观察重症肺炎患者病情变化情况，分析和研究血清降钙素原和C反应蛋白在治疗过程中的变化情况。方法将2010年5月～2013年5月间来河源市源城区人民医院就诊的86例肺炎患者根据病情的严重程度分为观察组和对照组，其中观察组患者43例，均为病情进展期重症肺炎患者，对照组患者43例为轻度肺炎患者，对比和分析2组患者治疗前后血清降钙素原和C-反应蛋白水平的改变情况及与预后的关系。结果重症肺炎组患者的血清降钙素原和C-反应蛋白水平显著高于轻度肺炎组患者，且比较差异具有统计学意义（P〈0.05）。结论对于重症肺炎患者其病情变化可将血清降钙素原和 C-反应蛋白水平作为观察指标并反映病情的严重程度。

Objective To observe the state changes of severe pneumonia patients better,as well as analyze and study the changes of serum procalcitonin and C-reactive protein during treatment . Methods Divided 86 cases of pneumonia patients treated in our hospital during May 2010 to May 2013 into observation group and control group according to the severity of illness, the patients of observation group（43 cases）were with severe pneumonia the control group, while the control group（43 cases） were with mild pneumonia,compared and discussed the changes and relationships with prognosis of serum procalcitonin and C-reactive protein level before and after treatment in the two groups. Results The serum procalcitonin and C-reactive protein levels of severe pneumonia patients were significantly higher than mild pneumonia patients, and the difference was statistically significant （P〈0.05）. Conclusion For patients with severe pneumonia,serum procalcitonin and C-reactive protein levels can adopt as observation target and reflect the severity of the disease.