88例老年患者梅毒螺旋体抗体筛查阳性结果的分析

Analysis of 88 Cases of Elderly Patients with Treponema Pallidum Antibody Positive Screening Results

目的探讨梅毒螺旋体抗体筛查阳性对老年患者的价值。方法采用化学发光法检测3520例老年患者血清中梅毒螺旋体抗体,阳性结果再用梅毒螺旋体明胶凝集试验(TPPA)和甲苯胺红不加热血清试验(TRUST)进行检测,对不确定标本再用免疫印迹(Western blot,WB)法进行最后确认。结果化学发光法共筛查出88例梅毒螺旋体抗体阳性,经TPPA确证阳性63例,TRUST阳性17例,当中TPPA确证均阳性。25例不确定标本,WB法确认1例阳性,7例可疑,17例阴性。结论老年患者梅毒螺旋体抗体筛查会有一定的假阳性,对单筛查阳性的标本应用免疫印迹法作最后确认。

Objective To investigate the value ofTreponema pallidum antibody screening positive for elderly patients. Method The detection of Treponema pallidum antibody in the serum of 3520 elderly patients by chemiluminescence method, and then the positive results of Treponema pallidum gelatin agglutination test （TPPA） and toluidine red unheated serum test （TRUST） for a test, antibody indeterminate samples by immunoblotting of Treponema pallidum （Western blot, WB） method for the final confirmation. Results The chemiluminescence method screening of 88 cases of syphilis antibody positive, confirmed by TPPA positive 63 cases, TRUST was positive in 17 cases, which were positive for TPPA validation. 25 cases were identified by uncertainty, WB was positive in 1 cases, 7 cases of suspected, negative in 17 cases. Conclusion Elderly patients with Treponema pallidum antibody screening will have certain false positive, final confirmation of a single screening positive samples by Western blotting.