中药系统的方法学──中药系统原理

Systematic Principle-Methodology of the System in Chinese Materia Medica

中药现代化的关键是自身庞大系统的方法学，即中药庞大数目的综合化学成分和复杂体系的整体药理作用的方法学。中药系统原理是处理中药庞大系统一般规律的方法学。中药系统原理以中药化学特征谱来表达综合活性成分，以基因组学和基因表达的细胞因子来揭示整体活性作用。

The key of the modernization of the Chinese materia medica is the methodology of the enormous and complex system of the Chinese materia medica itself, that is the methodology of the comprehensive chemical constituents and the whole pharmacological effects of the system. The systematic principle in Chinese materia medica is just the methodology dealing with the general rules of the enormous and complex system. The core of the systematic principle is how to wxpress and obtain the quantitative and controllable comprehensive chemical active constituents in stead of a single compound, and how to evaluate the whole pharmacological effects of the comprehensive constituents instead of a single effect. The systematic principle in Chinese materia medica expresses the comprehensive active constituents with the chemical feature spectra of Chinese materia medica, and exposes the whole pharmacological effects of the comprehensive constituents with genomics and cytokine expressed by genes and genomes.