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美沙拉嗪联合曲美布汀治疗肠易激综合征的临床观察 被引量:6

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摘要 目的探讨美沙拉嗪联合曲美布汀治疗肠易激综合征的临床疗效及安全性。方法选择符合标准的患者80例,随机分为观察组和对照组各40例,观察组应用美沙拉嗪联合曲美布汀治疗,对照组应用匹维溴胺联合谷维素,比较两组肠易激综合征症状改善情况。结果两组患者治疗前肠易激综合征症状评分比较,差异无统计学意义(P>0.05);治疗后两组患者评分较治疗前均下降(P<0.05),但是观察组下降幅度更大(P<0.05)。观察组患者显效22例、有效14例和无效4例;对照组显效10例、有效19例和无效11例,差异有统计学意义(P<0.05)。观察组患者不良反应发生率5.00%,对照组不良反应发生率10.00%,差异无统计学意义(P>0.05)。结论美沙拉嗪联合曲美布汀可以快速改善肠易激综合征的临床症状,提高临床治疗效果,安全性高,是一种治疗肠易激综合征的理想方法。
作者 凌智君
出处 《中国现代药物应用》 2014年第12期102-104,共3页 Chinese Journal of Modern Drug Application
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