ICU呼吸机相关性肺炎病原菌分布及耐药性监测

ICU ventilator-associated pneumonia pathogen distribution and drug resistance monitoring

目的:分析ICU呼吸机相关性肺炎(ventilator-associated pneumonia,VAP)病原菌,了解其分布及耐药性。方法:采集ICU收治的行有创机械通气治疗72h以上住院患者的痰样本,培养分离病原菌,药敏实验检测病原菌的耐药性。结果:ICU的VAP患者痰液分离菌株220株,革兰阴性菌占78.9%,耐药菌株比例高;鲍曼不动杆菌为常见感染菌,对碳青霉烯类药物的耐药率达68.4%。结论:ICU发生的VAP以非发酵菌为主,细菌耐药性严重。

Objective： To analyze ICU ventilator-associated pneumonia（VAP） pathogens and understand the distribution and drug resistance of them. Method： Sputum samples were collected from ICU inpatients who had been treated by invasive mechanical ventilation for more than 72 h inpatients, isolated pathogenic bacteria. Drug sensitivity test was done to detect drug resistance of pathogenic bacteria. Results： 220 strains were isolated from sputum of ICU patients with VAP, gram negative bacteria accounted for 78.9%, the high proportion of resistant strains; Bauman Acinetobacter was a common infection bacteria, their resistance to carbapenem rate reached 68.4%. Conclusion： ICU VAP is mainly infected by non fermenting bacteria, and their drug resistance is serious. Key words： ventilator-associated pneumonia ; pathogen ; drug resistance