慢性肛瘘并发非特异性溃疡性结直肠炎的临床诊治

Clinical diagnosis and treatment of chronic anal fistula complicated with non specific ulcerative

目的:探讨慢性肛瘘并发非特异性溃疡性结直肠炎的临床诊治措施。方法:慢性肛瘘并发非特异性溃疡性结直肠炎患者68例,随机分为观察组和对照组,每组各34例,对照组采用地塞米松及甲硝唑灌肠治疗,观察组采用地塞米松及甲硝唑灌肠的同时,联合采用黄芩、黄连、黄柏中药汤剂进行灌肠治疗,比较两组患者治疗效果。结果:治疗后,观察组患者腹痛、腹泻及肛门坠胀等临床症状的改善时间均短于对照组,差异有统计学意义(P<0.05)。观察组患者肠黏膜异常病理改善好,溃疡、炎性细胞浸润、隐窝脓肿、腺体异常等病例数,明显少于对照组,差异有统计学意义(P<0.05)。结论:西药联合中药汤剂进行灌肠治疗慢性肛瘘并发非特异性溃疡性结直肠炎,起效较快,效果好。

Objective. To explore the clinical diagnosis and treatment measures of chronic anal fistula associated with non specific ulcerative colitis. Methods： 68 cases of chronic anal fistula complicated with non specific ulcerative colitis patients, were randomly divided into observation group and con trol group, 34 cases in each group, the control group with dexamethasone and metronidazole enema treatment, observation group with dexamethasone and metronidazole enema, at the same time, the Huangqin, Coptis, Phellodendron Decoction enema treatment, effects of treatment were compared between the two groups. Results： After the treatment, the observation group patients were re- duced abdominal pain, diarrhea and anal bulge and other clinical symptoms, the improved time were shorter than that of the control group, the difference was statistically significant（P〈0.05）. Patients with abnormal intestinal mucosa pathology were improved, ulcer, inflammatory cell infil tration, crypt abscess, glandular abnormality cases were significantly less than that of the control group, the difference was statistically significant （P〈 0. 05）. Conclusion： Western medicine combined with traditional Chinese medicine, decoction for enema, is a good treatment for chronic anal fistula complicated with non specific ulcerative colitis, fast acting, good effect.