多西紫杉醇联合放疗用于中晚期鼻咽癌的疗效观察

Clinical observation of docetaxel combined with radiotherapy for advanced nasopharyngeal carcinoma patients

目的:观察多西紫杉醇联合放疗用于中晚期鼻咽癌的实际疗效,评价其临床应用价值。方法:回顾性分析42例中晚期鼻咽癌患者,按照治疗方式分为观察组21例,采用多西紫杉醇联合放疗进行治疗;以及对照组21例,采用单纯放疗进行治疗;比较两组患者治疗有效率及5年生存率。结果:应用多西紫杉醇联合放疗治疗的观察组临床改善明显优于对照组,治疗有效率及5年生存率组间差异均具有统计学意义(P<0.05)。结论:多西紫杉醇联合放疗用于中晚期鼻咽癌的治疗,具有疗效显著,安全可靠的特点,值得临床推广应用。

Objective：To observe the actual efficacy of paclitaxel combined with radiotherapy for advanced nasopharyngeal carcinoma patients, and to evaluate its clinical value. Methods： 42 patients with advanced nasopharyngeal carcinoma were divided into the observe group （21 cases, docetaxel combination with radiotherapy treatment）,and the control group （21 cases,radiotherapy treatment） in which effective rate and 5-year survival rate were compared in two groups . Results： The clinical improvement of the observation group was significantly better than that in control group. The effective rate and 5-year survival rate were statistically significant （P＆lt;0.05） between two groups. Conclusion： The docetaxel combined with radiotherapy for the treatment of advanced nasopharyngeal carcinoma has a significant effect,safe and reliable, and be worthy of clinical application.