105例胚胎停育绒毛细胞遗传学分析

Cytogenetic analysis of 105 cases embryo development arrest chorionic villus cells

目的探寻胚胎停育与绒毛细胞染色体异常的关系。方法收集2012年2014年2月佳木斯医学院105例胚胎停育患者,对其绒毛细胞进行培养和染色体核型分析。结果 105例胚胎停育患者,绒毛细胞培养失败6例,检出异常核型43例,染色体数目异常39例,染色体结构异常4例。结论胚胎绒毛细胞染色体异常是导致胚胎停育的重要原因。

Objective： To investigate the relationship between embryo development arrest and chorionic villus chromosomal abnormality. Methods： Collected 105 patients with embryo development arrest from 2012 to 2014 in February jiamusi medical college, to culture chorionic villus cells and their chromosomes were observed and analyzed. Results： 105 cases of embryo development arrest patients, villus culture failed to six cases, 43 cases of detected abnormal karyotype, 39 cases of an abnormal number, four cases of structural abnormalities. Conclusion： Embryonic chromosomal abnormality is an important reason for the embryo development arrest.