摘要
目的探讨中孕期超声筛查胎儿21-三体综合征与18-三体综合征的价值。方法 2011年1月~2013年6月在我院行羊水穿刺及脐血穿刺1562例病例,产前均在我院至少接受过一次超声检查,诊断21-三体儿22例,18-三体儿6例。孕妇年龄23~45岁,对其超声图像进行回顾性分析。结果本研究28例胎儿,除了7例21-三体儿超声未见明显异常外,另外15例21-三体儿与6例18-三体儿超声提示至少一个或一个以上的解剖结构异常或超声软指标。结论中孕期超声发现胎儿解剖结构畸形与超声软指标对于筛查21-三体与18-三体综合征具有重要的临床价值。
Objective： To assess the significance of the second trimester sonogram by analyzing its role in screening trisomy 21 and 18 syndromes. Methods： From Jan. 2011 to June 2013, data were analyzed about 1562 pregnant women who received amniocentesis and umbilical cord blood puncture. The study groups consisted of 22 fetuses with trisomy 21 and 6 fetuses with trisomy 18. A retrospective study was carried out on the sonogram of pregnant women aged between 23 and 45. Results： At least one or more than one abnormal fetal sonograms were detected in 15 trisomy 21 fetuses and 6 trisomy 18 fetuses. Conclusion： Second trimester ultrasound plays an important role in screening trisomy 21 and trisomy 18.
出处
《中国优生与遗传杂志》
2014年第6期48-49,F0004,共3页
Chinese Journal of Birth Health & Heredity
