高压氧在治疗糖尿病视网膜病变中的应用进展

Advances of Hyperbaric Oxygen Therapy in Diabetic Retinopathy

糖尿病视网膜病变是糖尿病最常见、最主要的微血管并发症之一,其高发病率、高致盲率特征严重威胁着人类的健康和生存质量。长期的高糖状态导致视网膜缺血缺氧是糖尿病视网膜病变的主要发病原因。控制高血糖和改善组织缺氧无疑是防治糖尿病微血管病变的有效方法之一。而高压氧治疗是许多急慢性疾病的首选或辅助治疗方法。已有大量证据表明,高压氧治疗对视网膜静脉阻塞及黄斑囊样水肿、缺血性视神经病变、中心性浆液性脉络膜视网膜病变等眼病安全有效。本文就高压氧在糖尿病视网膜病变中的应用进行综述和讨论。

Diabetic retinopathy （DR） is one of the most common and severe microvascular complications of diabetes mellitus. The characteristics of high incidence rate and high blinding rate affects the health and quality of life seriously. Long-term high sugar state can cause retinal ischemia and oxygen Which is the main reason of Diabetic retinopathy. So control hyperglycemia and improve the hypoxia is undoubtedly the prevention and control of diabetes microvascular lesions one of the effective ways. Hyperbaric oxygen therapy is aprmiary or adjuvant therapeutic method for various acute or chronic diseases .There are substantial evidences showing its safety and efficacy in many eye diseases such as retinal vein occlusion and hemorrhagic optic neuropathy, central serous retinopathy choroid, etc. This paper hyperbaric oxygen in diabetic retinopathy were reviewed and discussed the application.In the present review, we will focus on the concept of advances of hyperbaric oxygen therapy in diabetic retinopathy.