丹参饮合四妙勇安汤化裁对心血瘀阻证慢性稳定性心绞痛心肌缺血总负荷变化的临床观察

The Clinical Therapeutic Effect of Red Sage Combination and Simiao Yong'an Decoction on Total Ischemia Burden of Patients of Chronic Stable Angina

[目的]观察丹参饮合四妙勇安汤化裁对心血瘀阻证慢性稳定性心绞痛(chronic stable angina,CSA)心肌缺血总负荷(total ischemia burden,TIB)的临床疗效。[方法]将2012年5月至2013年4月符合诊断标准的60例心血瘀阻证CSA患者随机分为对照组、治疗组两组,各30例,对照组用拜阿斯匹林加倍他乐克及洛汀新治疗,治疗组在对照组治疗基础上加用中药丹参饮合四妙勇安汤化裁治疗,以动态心电图检查治疗前及治疗1个月后的TIB结果并行比较。[结果]治疗1个月后,两组TIB均明显降低,同组治疗前后比较差异有统计学意义(P<0.05);与对照组比较,治疗组治疗后TIB降低更为明显,两组比较差异有统计学意义(P<0.05)。[结论]丹参饮合四妙勇安汤化裁对心血瘀阻证CSA患者的TIB的临床疗效明显,值得临床推广应用。

[Objective]To observe the clinical therapeutic effect on total ischemia burden（TIB） of myocardial ischemia of patients of chronic stable angina treated by Red Sage Combination and Simiao Yong＇an Decoction.[Method]Divide 60 standard cases from 2012 May to 2013 April randomly into control group（30） and treatment one（30）,the control one was treated with BaiAspirin and Beitaleke and Luotingxin,the treatment one was treated with Red Sage Combination and Simiao Yong＇an Decoction and routine therapy.Then,compare the TIB results between pretherapy and 1 month later by HOLTER examination.[Result]The result showed,after 1-month treatment,there＇s difference in HOLTER examination of TIB between before and after treatment,with marked meaning（P〈0.05）.Compared with the control group,the TIB results of treatment group decreased more obviously after treatment and there was significant difference between two groups（P〈0.05）.[Conclusion] Red Sage Combination and Simiao Yong＇an Decoction have obvious improvement in TIB,worthy to be recommended its clinical use.