肺动脉高压干细胞移植治疗的研究进展

Study Progress of Stem Cell Transplantation Therapy on Pulmonary Arterial Hypertension

肺动脉高压是临床较常见的疾病,死亡率很高,目前主要采用抗凝剂和血管扩张剂治疗,但是效果不理想,无法改变肺血管重塑,不能改善预后。通过移植干细胞形成新生血管取代病变的肺动脉血管,建立侧支循环,有效减轻肺动脉高压和肺组织病变程度,有望治愈本病。

Pulmonary hypertension is more common clinical disease, high mortality, mainly using antico- agulant and vasodilator therapy, but the result is not satisfactory, you can not change the pulmonary vascular remodeling can improve the prognosis. The formation of new blood vessels by transplanting stem cells to replace the pulmonary vascular lesions, the establishment of collateral circulation, effectively reducing the degree of pulmonary hypertension and lung tissue lesions. Can cure completely the disease.