摘要
目的:优选中药复方制剂萎康胶囊的提取工艺。方法:采用正交试验法,以淫羊藿苷、总黄酮醇苷的含量以及干膏得率作为考察指标,对乙醇浓度、乙醇用量、提取时间、提取次数4个因素进行考察,并结合综合评价的方法优选出萎康胶囊的提取工艺。结果:最佳提取工艺:12倍量60%乙醇,回流提取3次,每次1 h。结论:优选出的萎康胶囊提取工艺稳定可行、科学合理,可用于工业化大生产。
This study was aimed to optimize the extraction technology of Wei-Kang （WK） Capsule. Orthogonal test and comprehensive evaluation were used to optimize the extraction process of compound preparation. The icarrin, to-tal ginkgo flavone glycosides and the dried decocting rates were used as index components for optimizing the effect of ethanol concentration, ethanol volume, extraction duration and extraction frequency. The results showed that the opti-mal ethanol extraction technology was adding 12 times of 60% ethanol and extract for 3 times with 1 h for each ex-traction time. It was concluded that the optimized extraction technology was stable, practical, scientific and reason-able, which can be used in the large-scale industrial production.
出处
《世界科学技术-中医药现代化》
北大核心
2014年第5期1188-1192,共5页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
关键词
萎康胶囊
淫羊藿
银杏叶
正交试验
提取工艺
Wei-Kang Capsule
Epimedium brevicornum
leaves of ginkgo biloba
orthogonal test
extraction technology
