2-噻吩基苯酚的合成路线

Synthetic Methods of 2-(Thiophen-2-yl)Phenol

探究了7种合成2-噻吩基苯酚的路线.以2-溴-苯甲醚和2-溴噻吩为原料,通过Kumada偶联反应,以65%的产率获得98%纯度的产物.

After exploring seven different reaction routes of 2-（thiophen-2-yl）phenol,the article comes up with an innovative synthetic way by Kumada coupling reaction,which takes 2-Bromoanisole and 2-bromo thiophene as raw materials.The yield reaches to 65% with the purity of 98%.