终末期肝病模型在临床中的研究进展

The research progress of model for end-stage liver disease in clinic

目前原发性肝癌的治疗仍以手术切除为首选。手术后有可能出现肝功能不全甚至肝功能衰竭导致患者死亡。因此,术前正确评估肝脏的储备功能,对选择合理的治疗方法,把握合适的肝切除范围,减少术后肝衰竭的发生率具有重要意义。鉴于CTP分级存在诸多不足,美国学者建立了新的评价体系——终末期肝病模型(MELD)评分系统。本研究就MELD在临床中研究进展做一综述。

Surgical resection still is the first choice of the treatment for primary liver cancer currently. It＇s possible to appear hypohepatia and liver failure which will lead to death after operation. Therefore, accurate evaluation of the preoperative liver functional reservation is significant to choose rational treatment, to grasp the safe resection range of liver, to reduce the incidence of postoperative liver failure. Given many shortcomings of CTP classification, American scholars have established a new evaluation system-the model for end-stage liver disease （MELD） score system. This article will summarize about MELD progress in clinic.