41例小剂量罗红霉素联合氨茶碱治疗支气管扩张的疗效分析

The Curative Effect Analysis of Small Dose of Luo Erythromycin Combined with Aminophylline in the Treatment of Bronchiectasis of 41 Cases

目的:研究小剂量罗红霉素联合氨茶碱治疗支气管扩张的临床效果。方法:选取82例支气管扩张患者作为研究对象,按照随机数字表法分为观察组和对照组,每组41例。观察组给予小剂量罗红霉素联合氨茶碱治疗,对照组则单纯采用罗红霉素治疗。比较两组的治疗效果,包括治疗前后痰量、发作次数、肺功能改善情况、治疗有效率、不良反应等。结果:观察组的痰量、发作次数、肺功能改善情况明显优于对照组,两组比较差异均有统计学意义(P<0.05)。观察组的治疗总有效率为97.6%,明显高于对照组的78.0%,两组比较差异有统计学意义(P<0.05)。但两组不良反应发生情况比较差异无统计学意义(P>0.05)。结论:使用小剂量罗红霉素联合氨茶碱治疗支气管扩张安全有效,不良反应少,值得推广。

Objective：To study the small dose of luo erythromycin combined with aminophylline in treatment of bronchiectasis.Method： Selected 82 cases of patients with bronchiectasis as the research object, and randomly divided into the observation group and the control group, each group of 41 cases. The observation group was treated by small dose of Luo Erythromycin combined with Aminophylline. The control group was treated only by Luo Erythromycin. Comparative analysis of two groups of treatment effect, including sputum volume before and after the treatment, attack times, improve lung function, treatment effectiveness and adverse reactions.Result： The observation group of sputum volume, attack times, improve lung function was better than the control group, and the difference between the two groups were all statistically significant（P〈0.05）. The effective rate of the control group was 78.0% while the observation group was 97.6% after treatment, and the difference between the two groups were statistically significant（P＆lt;0.05）. But no obvious difference was found between two groups of adverse reaction happening（P〉0.05）.Conclusion： Using small doses of Luo Erythromycin union Aminophylline treatment of bronchiectasis is safe and effective, less adverse reactions, worthy of promotion.