妊娠并尖锐湿疣是否需终止妊娠及治疗分析

Analysis of Necessity of Pregnancy Termination and Treatment for Pregnant Patients with Condyloma Acuminatum

目的探讨妊娠并尖锐湿疣(condyloma cuminatum,CA)对妊娠结局的影响及有效的治疗方法。方法选择妊娠期CA终止妊娠63例(终止妊娠组)、妊娠期CA继续妊娠65例(继续妊娠组)及非妊娠期CA 50例(对照组),均采用电离子术治疗,比较3组术后7 d治愈率、术后3个月复发率,并统计继续妊娠组的妊娠结局。结果终止妊娠组、继续妊娠组、对照组术后7 d治愈率分别为87.30%、86.15%、88.00%,差异无统计学意义(P>0.05);术后3个月复发率分别为15.87%、36.92%、14.00%,继续妊娠组明显高于其他两组(P<0.05);3组总治愈率均为100%。继续妊娠组均选择剖宫产结束分娩,新生儿均足月存活,无胎儿宫内发育迟缓、新生儿喉乳头状瘤、生殖器疣及肛门疣等发生。结论妊娠并CA可以继续妊娠,电离子手术治疗妊娠期CA安全、可靠,患者妊娠结局良好。

Objective To explore the influence of condyloma acuminatum（ CA） on pregnancy outcome and the effective method for clinical treatment. Methods The electrocautery therapy was performed for 63 pregnant women with CA who terminated pregnancy（ group A）,65 pregnant women with CA continued pregnancy（ group B） and 50 non pregnant women with CA（ control group）. The recovery rate 7 d after the operation and recurrence rate 3 months after the operation were compared in the three groups,and pregnancy outcomes in group B were analyzed. Results The recovery rate 7 d after the operation in group A,B and control group were 87. 30%,86. 15% and 88. 00% respectively,and there were no statistically significances（ P 0. 05）; the recurrence rate 3 months after the operation were 15. 87%,36. 92% and 14. 00% respectively,and the recurrence rate in group B was significantly higher than those in the other two groups（ P 0. 05）; the total recovery rates in the three groups were all 100%. Patients in group B all underwent cesarean,all full-term newborns were live births,and there were no intrauterine growth retardation,newborn laryngeal papilloma,genital warts and anal warts. Conclusion Pregnant women with CA can continue pregnancy,and electrocautery in treatment of CA during gestation period is safe and reliable with good pregnancy outcomes.