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骨质疏松症的药物治疗进展 被引量:4

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摘要 随着社会老龄化的到来,骨质疏松症(OP)的发病率逐年提高。近几十年骨质疏松的药物治疗获得较大进展。钙剂及维生素D是骨质疏松症的基础药物,所有患者均应推荐使用。激素类药物因其严重不良事件,不能作为OP的一线治疗用药。二磷酸盐类、降钙素类临床应用较广,疗效肯定,用药依从性欠佳,也存在一些不良事件。新的抗OP药物,如狄诺塞麦、特立帕肽、组织蛋白酶K抑制剂、Src激酶抑制剂等或许会有更好的疗效及用药依从性,但其长期使用的安全性尚需进一步临床验证。本文就OP的药物治疗进行综述,为临床医师治疗OP提供参考。
出处 《医学理论与实践》 2014年第11期1428-1430,共3页 The Journal of Medical Theory and Practice
基金 上海市残疾人康复科研资助项目(k2012035)
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