米托蒽醌在离子注入修饰电极上的伏安行为及其应用

Studies on the Voltammetric Behavior of Mitoxantrone and Its Application at the Ni/GC Modified Electrode

在 0 .1 mol/L NH3 -NH4 Cl缓冲溶液 ( p H9.5)中 ,米托蒽醌在镍离子注入修饰电极上有一灵敏的伏安还原峰 ,峰电位为 -0 .85V( vs.SCE) .峰电流与米托蒽醌的浓度成线性关系 .检出限为 1 .8× 1 0 -8mol/L.研究了其伏安行为 ,并将该波用于尿样的测定 .结果表明 ,还原过程为具有吸附性和催化性的准可逆过程 .AES和 XPS实验表明 ,Ni已注入到玻碳电极的表面 。

In a 0 1 mol/L NH 3 NH 4Cl buffer solution(pH 9 50), a sensitive reduction peak of mitoxantrone at a Ni/GC modified electrode was obtained by linear sweep voltammetry. The peak potential was -0 85 V( vs . SCE). The peak current was proportional to the concentration of mitoxantrone. The detection limit was 1 8×10 -8 mol/L. Its voltammetric behavior was studied and the wave was applied to the determination of mitoxantrone in urine. The reduction process was quasi reversible with adsorption and catalysis. AES and XPS experiments showed that Ni was surely implanted into the surface of the GCE, and the implanted Ni at the GC improved the electrocatalytic activity.