基于含Ni稀土钙钛矿LaNiTiO_3的过氧化氢无酶传感器

A Nonenzymatic Sensor for H_2O_2 Detection Based on Rare-earth Perovskite LaNiTiO_3 Containing Ni

合成了一种含Ni的新型稀土钙钛矿纳米氧化物LaNiTiO3,研究了其催化活性,并以此构建了一种简单、快速、性能稳定的检测过氧化氢(H2O2)无酶电化学传感器。采用X-射线衍射仪、傅立叶红外光谱仪、透射电子显微镜、X-射线荧光光谱仪以及扫描电子显微镜等手段对合成材料的组成、结构和形貌等进行了表征,并通过循环伏安法和电流-时间曲线研究和优化了基于该材料构建的无酶传感体系。结果表明,以LaNiTiO3(0.5 g/L,8.0μL)修饰的工作电极在0.1 mol/L NaOH中对H2O2呈现良好的电催化性能:响应时间短(约2 s)、线性范围宽(0.2μmol/L^8.0 mmol/L)、检出限低(0.05μmol/L,S/N=3)、灵敏度高(957μA·L·mmol!1cm!2)、重现性好和抗干扰能力强,优于最近报道的其它传感器,有望用于生物医学等实际样品H2O2检测分析中。

A Ni-based rare-earth perovskite LaNiTiO3nanoparticles was synthesized and its catalytic activity was investigated. Based on this,a simple and quick nonenzyme electrochemical sensor was fabricated with stable and reliable performances for the determination of hydrogen peroxide（ H2O2）. The techniques of X-ray diffraction,FT-IR spectra, transmission electron microscopy, X-ray fluorescene spectroscopy and scan electronmicroscope were used to characterize the composition,structure and morphology of as-synthesized sample. The sensor based on this nanomaterial was investigated and optimized by cyclic voltammetry and current-time techniques. The results showed the working electrode modified with LaNiTiO3（0. 5 g/L,8. 0 μL） in 0. 1 mol/L NaOH exhibited good catalytic properties for H2O2. Under the optimum conditions,the sensor performed excellent properties, such as quick response time（ about 2 s）, a wide linearity（0. 2 μmol/L-8. 0 mmol/L）,a low detection limit of 0. 05 μmol/L（S/N = 3）,a high sensitivity of 957 μA（ mmol / L）^-1cm^-2,good reproducibility and anti-interference ability,which was better than those of some other biosensors reported recently. So,it may be used for the analysis and detection of H2O2in practical samples such as biomedicine.