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早期应用硫酸镁治疗弥漫性轴索损伤70例临床疗效分析 被引量:5

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摘要 目的探讨硫酸镁治疗弥漫性轴索损伤的临床疗效。方法将70例弥漫性轴索损伤患者按随机数字法分为治疗组和对照组。治疗组在常规治疗的基础上,早期即伤后6小时内将25%硫酸镁8ml用生理盐水稀释至100ml后匀速静脉推注,时间约为15分钟,再用25%硫酸镁30ml加入5%葡萄糖500ml中24小时缓慢静脉滴注,用输液泵控制输液速度,连用7d。对照组采用常规治疗。对两组患者3个月后恢复情况采用GOS预后评分进行比较。结果 3个月后对照组GOS评分为2.39±1.52,治疗组GOS评分为3.41±1.58,治疗组显著高于对照组(P<0.05)。结论早期应用硫酸镁能显著改善弥漫性轴索损伤患者的预后,保护神经功能。
出处 《浙江创伤外科》 2014年第3期460-461,共2页 Zhejiang Journal of Traumatic Surgery
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