β,γ-不饱和酮酸酯与亚甲胺叶立德的[1,3]-偶极环加成反应

1,3-Dipolar Cycloaddition Reaction of Azomethine Ylide with β,γ-Unsaturated Keto esters

运用β,γ-不饱和酮酸酯与亚甲胺叶立德的[1,3]-偶极环加成反应合成一系列恶唑烷类衍生物,在室温下就可以得到非常好的化学收率,最高收率达92%.

oxazolidine derivatives were syntesized through [1,3]-dipolar cycloaddition reaction of β,γ-unsaturated ketoesters with azomethine ylide,generating in situ from N-（methoxymethyl）-N-（trimethylsilylmethyl） benzylamine,offering the 1,3-dipolar cycloaddition products in high yields.