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西地那非联合肺表面活性物质治疗足月儿呼吸窘迫综合征并持续肺动脉高压效果观察 被引量:1

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摘要 目的观察机械通气下西地那非联合肺表面活性物质(固尔苏)治疗足月儿呼吸窘迫综合征(N R D S)合并持续肺动脉高压(P P H N)的效果。方法 N R D S合并P P H N患儿1 5例随机分为观察组8例和对照组7例。两组均常规常频机械通气及固尔苏治疗,观察组加用西地那非;比较两组肺动脉平均压力(PAMP)、血气指标、呼吸机使用时间。结果治疗后观察组血气情况好于对照组,机械通气时间及住院时间短于对照组,差异均有统计学意义。两组治疗后低氧血症均有较大程度改善,P A M P明显缩小。结论机械通气下西地那非联合固尔苏治疗N R D S合并P P H N,可明显缩短机械通气治疗时间,从而减少住院费用,适合基层医院使用。
出处 《中国乡村医药》 2014年第11期13-14,共2页
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