摘要
目的观察健身舞对老年人免疫、呼吸及循环功能的影响。方法选取100名健身舞老年人作为锻炼组,100名不参与锻炼的老年人作为对照组,分别于运动前、运动后即刻和运动后2h,测定Ca2+浓度、Bcl-2基因蛋白表达、细胞凋亡率以及相关免疫参数。同时测定锻炼前、后老年人每搏输出血量、每分输出血量、射血分数、心率等心脏泵血功能指标,流入时间和波幅等阻抗血流图指标,肺活量、每分最大通气量等肺通气功能指标。结果与对照组比较,锻炼组安静状态下Ca2+浓度显著降低,Bcl-2基因蛋白表达有所升高,淋巴细胞凋亡率降低。在锻炼组,与运动前比较,运动后即刻CD3+、CD4+、CD4+/CD8+比值均有所升高,CD8+和CD16+56+降低;运动后2h血液中的CD3+、CD4+、CD4+/CD8+继续升高,CD8+从低转高,CD16+56+持续下降;锻炼后,每搏输出量和射血分数较锻炼前显著增加,心率减慢,而流入时间明显缩短且波幅增大,肺活量及每分最大通气显著增加。结论适度的老年健身舞运动可以有效增强老年人机体免疫应答过程,维持Ca2+浓度稳定状态,确保细胞生存状态有序化、稳定化、正常化,并且明显改善老年人呼吸和心脑血液的循环功能,对促进老年人身体健康具有积极意义。
Objective To observe the effect of elderly fitness dance movement on the immune,respiration and cardiovascular cir-culatory function in old people.Methods The 100 elderly people engaging in elderly fitness dance movement were selected as the train group and 100 elderly people without engaging in physical exercise were selected as the control group.The vein blood was col-lected before exercise,immediately after exercise and at 2 h after exercise.The Ca2+concentration,Bcl-2gene protein expression,ap-optosis rate and related immune indexes.The heart pump function index such as every cardiac output volume,output volume,ej ec-tion fraction and heart rate,etc.impedance blood flow index such as inflows of time and amplitude,etc.pulmonary ventilation func-tion index such as the vital capacity,every maximal ventilatory volume etc.before and after exercise were detected.Results Com-pared with the control group,Bcl-2 gene protein expression was increased,the Ca2+ level and lymph cell apoptosis rate were de-creased under the resting state in the train group.Compared with before exercise,CD3+,CD4+ and CD4+/CD8+ ratio were in-creased,and CD8+ andCD1 6+5 6+ were decreased immediately after exeercise in the train group;at 2 h after exercise,CD3+,CD4+and CD4+/CD8+ ratio continuously increased,CD8+ was converted from low to high and CD1 6+5 6+ was continously decreased;af-ter exeercise,the stroke volume and the ej ection fraction were significantly increased compared with before exercise,the heart rate was decreased,the inflow time was obviously shortened and the amplitude was enlarged,the vital capacity and the maximal breath-ing capacity were significantly increased after exercise.Conclusion Moderate elderly fitness dance movement can effectively in-crease the immune response,maintain the stable state of Ca2+concentration,ensure ordering,stabilization and normalization of cell living status and improve the respiratory and cardiovascular circulatory function of elder people,which has positive significance for promoting the physical health of elderly people.
出处
《重庆医学》
CAS
CSCD
北大核心
2014年第18期2275-2277,共3页
Chongqing medicine
关键词
老年人
免疫
呼吸
循环
健身舞
aged
immunologic
respiratory
circulatory
fitness-dance