血浆同型半胱氨酸水平与心肌梗死的相关性

Relationship of plasma homocysteine level with myocardial infarction

目的探讨血浆同型半胱氨酸(Hcy)水平与心肌梗死的关系。方法我院2012年1月至2013年12月间收治的40例心肌梗死患者作为心肌梗死组,选取同期行健康体检的正常人40例作为非心肌梗死组,比较两组血浆Hcy水平及治疗后心肌梗死组患者Hcy水平,分析心肌梗死危险因素。结果心肌梗死组患者血浆Hcy水平明显高于非心肌梗死组,治疗后,心肌梗死组Hcy水平较治疗前有明显下降,差异均具有统计学意义(P<0.05);血浆Hcy高表达为心肌梗死独立危险因素。结论血浆Hcy水平与心肌梗死有一定的相关性,高Hcy为心肌梗死的独立危险因素。

Objective To investigate the relationship of plasma homocysteine （Hcy） level with myocardial infarction. Methods Forty patients with myocardial infarction admitted to our hospital from January 2012 to December 2013 were selected as myocardial infarction group, and 40 healthy persons who underwent physical examination in the same period were selected as non-myocardial infarction group. The two groups were compared in terms of plasma Hcy levels, and the changes in the Hcy levels of patients with myocardial infarction after treatment were evaluated. The risk factors for myocardial infarction were analyzed. Results The myocardial infarction group had significantly higher plasma Hcy levels than the non-myocardial infarction group. After treatment, the myocardial infarction group showed a significant decrease in Hcy levels （P〈0.05）. High expression of plasma Hcy was an independent risk factor for myocardial infarction. Conclusion Plasma Hcy level is related to myocardial infarction. High Hcy level is an independent risk factor for myocardial infarction.