过敏性疾病患者血清维生素D的营养状况

VITAMIN D STATUS IN PATIENTS WITH ALLERGIC DISEASES

目的通过检测和分析过敏性疾病患者血清维生素D水平,以探讨维生素D缺乏是否为过敏性疾病发病的影响因素,为过敏性疾病的预防和治疗提供一定的依据。方法选择过敏性疾病患者208例(儿童128例,成人80例),应用电化学发光法检测其血清中25-羟维生素D(25-(OH)D)的水平,分析其缺乏率、不足率并与相应儿童、成人对照组进行比较。结果过敏性疾病儿童患者组血清维生素D水平低于儿童对照组,维生素D缺乏率高于对照组,差异均具有显著性(P<0.05)。而过敏性疾病成人患者组血清维生素D水平、维生素缺乏及不足率与成人对照组相比均无显著性差异(P>0.05)。结论维生素D缺乏与儿童过敏性疾病的发病有一定的关系,而维生素D水平在成人过敏性疾病中无明显异常,适当的补充维生素D可能有助于儿童过敏性疾病的预防与治疗。

Objective To study the clinical significance of vitamin D in allergy diseases by measuring the serum level of vitamin D. Methods The serum level of vitamin D was measured by electrochemiluminescence in 208 cases of allergy disease（128 children and 80 adults）. The deficient rate and insufficient rate in children and adult patients were compared to the controls respectively. Results The deficient rate in children patients was higher than that in controls. Serum vitamin D level in children patients was significantly lower than that in controls（P〈0.05）. However, there was no significant difference in the deficient rate and serum vitamin D level in adult patients and their controls. Conclusion Vitamin D deficiency might be related to the children allergy diseases, and supplementation of vitamin D may be helpful for prevention and therapy of allergy diseases.