红细胞免疫及红细胞参数在充血性心力衰竭患者中的检测价值

Study on the value of erythrocyte immune and erythrocyte parameters in patients with congestive heart failure

目的探讨红细胞免疫及红细胞参数在充血性心力衰竭患者中的检测价值。方法选取2011年7月至2013年10月本院收治的65例充血性心力衰竭患者为观察组,65名健康人员为对照组,然后将两组的红细胞免疫及红细胞参数检测结果进行比较,同时比较NYHA分级Ⅱ级、Ⅲ级及Ⅳ级充血性心力衰竭患者的上述检测指标。结果观察组的协同肿瘤红细胞花环率(ATER)、自然肿瘤红细胞花环率(NTER)、红细胞免疫粘附肿瘤细胞(RIT)、免疫粘附促进因子(FEER)及血红蛋白(Hb)、红细胞计数(RBC)均低于对照组,免疫粘附抑制因子(FEIR)及红细胞分布宽度(RDW)高于对照组。NYHA分级Ⅳ级患者的ATER、NTER、RIT、FEER及Hb、RBC均低于Ⅱ级和Ⅲ级患者,Ⅲ级患者则低于Ⅱ级患者,NYHA分级Ⅳ级患者的FEIR及RDW高于Ⅱ级和Ⅲ级患者,Ⅲ级患者则高于Ⅱ级患者,以上各项检验指标比较差异均有统计学意义(P<0.05)。结论红细胞免疫及红细胞参数在充血性心力衰竭患者中的检测价值较高,且对于NYHA分级的了解也有一定的价值。

Objective To investigate and study the detection value of erythrocyte immune and etythrocyte parameters in patients with congestive heart failure. Methods Sixty-five patients with congestive heart failure in our hospital from July 2011 to October 2013 were enrolled as observation group and another 65 healthy persons were se- lected as control group. The erythrocyte immune and erythrocyte parameters ＂m both groups were compared. Mean- while, those detection indexes in patients with NYHA grade Ⅱ, grade ⅡⅢ and grade IV were compared. Results The associated tumor erythrocyte rossette （ATER）, natural tumor erythrocyte rossette （NTER）, RBC immune adherence tu- mor cell （RIT）, immune adherence enhance factor （FEER） and hemoglobin （Hb）, red cell count （RBC） in observation group were all lower than those in control group. And immune adherence inhibitor factor （FEIR） and red cell distribu- tion width （RDW） were higher than those in control group. Furthermore, the ATER, NTER, RIT, FEER, Fib and RBC in patients with NYH grade IV were lower than in those with grade Ⅱ and grade Ⅲ. And those indexes in patients with grade Ⅲ were lower than in those with grade Ⅱ. However, the FEIR and RDW in patients with NYHA grade IV were higher than in those with grade Ⅱ and grade Ⅲ, and those indexes in patients with grade Ⅲ were higher than in those with grade Ⅱ. All the differences were statistically significant （P〈0.05）. Conclusion The detection value of crythrocyte immune and erythxocyte parameters in patients with congestive heart failure is high, and it has certain val- ue for understanding NYHA grade.