建立药物利用评估标准评价风湿内科患者糖皮质激素类药物用药情况

Establishment of DUE Standard for Evaluating the Application of Glucocorticoids in Rheumatisants

目的:建立适用于医院风湿内科患者使用糖皮质激素类药物的药物利用评估(DUE)标准,对糖皮质激素类药物使用的合理性进行评价。方法:通过DUE标准基本框架的构建,结合查阅文献和参考《糖皮质激素临床应用指导原则》,建立糖皮质激素类药物的DUE标准,设计数据收集表收集我院风湿内科2011年10月-2012年3月101例使用糖皮质激素类药物的患者的病例资料,评估该类药物的使用情况。结果:所涉及8种糖皮质激素类药物,药物相互作用不合理13例,给药疗程不合理6例,药物剂量不合理4例。结论:我院风湿内科在使用糖皮质激素类药物的治疗过程中存在不合理用药情况,通过建立DUE标准,可促进糖皮质激素类药物的合理应用,提高临床药学服务水平。

OBJECTIVE： To establish DUE standard which is suitable for evaluating the application of glucocorticoids in rheu- matisants, and to evaluate the rationality of glucocorticoids use. METHODS： Through the construction of the basic framework of DUE standards, combining with the experts consulting and guidance for clinical application of glucocorticoid, DUE standard for glucocorticoids was established, and medical information of 101 patients receiving glucocorticoid in rheumatology department of our hospital of TCM during Oct. 2011 to Mar. 2012 were collected by designing the data collection form, and the use of glucocorticoid was evaluated. RESULTS： 8 kinds of glucocorticoids were involved; there were 13 cases of irrational drug interaction, unreasonable 6 cases of treatment course and 4 cases of irrational drug dosage. CONCLUSIONS： There is irrational drug use in the process of glucocorticoid treatment in rheumatology department of the hospital. The establishment of DUE can promote reasonable use of glueocorticoids and improve the level of pharmaceutical care.