改良去大骨瓣减压术治疗恶性大脑中动脉脑梗死

Modified large craniectomy decompression in the treatment of malignant middle cerebral artery infarction

目的：探讨改良去大骨瓣减压术治疗恶性大脑中动脉脑梗死的治疗效果与预后。方法选取2010年7月-2013年7月我院采用改良去大骨瓣减压术治疗的恶性大脑中动脉脑梗死患者40例为治疗组；回顾性分析我院2006年7月-2009年7月采取传统去骨瓣减压手术治疗的脑梗死患者40例为对照组，比较两组患者的恢复期表现、疗效和预后。结果治疗组患者生存率90.00%（36/40），显著高于对照组的57.50%（23/40），差异有统计学意义（P＜0.05）；治疗组术后并发症显著低于对照组，差异有统计学意义（P＜0.05）。结论改良去大骨瓣减压术治疗恶性大脑中动脉脑梗死患者不仅可明显提升治疗效果，还可减少术后并发症，安全性好，值得临床推广。

Objective To explore the therapeutic effect and prognosis of modified large craniectomy decompression in the treatment of patients with malignant middle cerebral artery infarction. Methods Forty malignant cerebral artery in-farction patients were treated with modified large craniectomy decompression from July 2010 to July 2013 in our hospi-tal , set as the treatment group; retrospective analyzed 40 cerebral infarction patients in our hospital from July 2006 to July 2009 which were adopted traditional operation bone flap decompression treatment as the control group. The recov-ery stage, the rapeutic effect and prognosis were compared between two group patients. Results The survival rate in the treatment group was 90%（36/40）,and was significantly higher than 57.50%（23/40） in the control group, the differ-ence was statistically significant （P〈0.05）;Postoperative complications in treatment group were significantly lower than the control group,the differences were statistically significant（P〈0.05）. Conclusion Modified large craniectomy decom-pression in the treatment patients with malignant middle cerebral artery infarction ,can significantly improve the thera-peutic effect, and reduce postoperative complications, the safety is excellence,and is worth the clinical promotion.