摘要
呼吸道菌群研究是一个相对较新的领域,随着16S rRNA序列分析检测技术在临床研究中的广泛应用,人们对呼吸道菌群失调与支气管哮喘发生发展之间的关系有了新的认识,研究发现呼吸道有着远比之前认识要多样化的菌群.呼吸道菌群异常可能是支气管哮喘发生及加重的潜在原因之一.
Researches of the airway microbiome represent a new frontier in pulmonary research.Detection and identification of microorganisms by 16S rRNA gene sequence has been widely used in clinical studies.The new understanding of the relationship between bronchial mibrobiota and development or presence of asthma is recognized.A far more diverse microbiota is observed now.Altered airway microbiome may have a potential role in the development of asthma,as well as in asthma exacerbations.
出处
《国际呼吸杂志》
2014年第13期1024-1027,共4页
International Journal of Respiration
基金
教育部留学回国人员科研启动基金
广州呼吸疾病研究所开放课题（AS0154F1104）
关键词
呼吸道
菌群失调
支气管哮喘
Airway
Altered microbiome
Bronchial asthma
