哺乳动物克隆的研究进展与应用前景

New Advances and Future Perspectives in Mammal Cloning

显微注射技术本身固有的缺点在很大程度上限制了转基因动物的研究及应用。近年来 ,体细胞基因打靶和体细胞克隆的最新研究进展表明 ,这两种技术相结合将成为制备大型转基因动物的有效途径。

To the great extent,the study and application of transgenic animal are restricted by the inherent limitation of pronuclear microinjection.Recently,the rapid progresses in gene targeting and cloning of somatic cells have shown that the combination of these two technologies will become a virtual way to producing large transgenic animals.