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DDR1的激活及其信号通路研究进展

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摘要 盘状结构域受体(discoidin domain receptors,DDRs)是一类受体型酪氨酸激酶(receptor tyrosine kinases,RTKs),可分为DDR1和DDR2,在细胞的黏附、增殖及细胞外基质的重塑中起重要作用.大量研究表明,DDR1及其信号通路在肿瘤的发生、发展中发挥重要作用.本文对DDR1的激活及其相关信号转导通路的研究进展综述如下。
出处 《徐州医学院学报》 CAS 2014年第6期418-420,共3页 Acta Academiae Medicinae Xuzhou
基金 国家自然科学基金(81301806)
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