摘要
通过熔融共缩聚反应,将1∶1和1∶2两种摩尔比的丙三醇和癸二酸合成可生物降解的聚癸二酸丙三醇聚酯弹性体(PGS),并对其性能进行测定,1∶1组PGS与左旋聚乳酸(PLLA)共混,应用静电纺丝方法构建组织工程支架。结果表明,PGS弹性体具有优异的亲水性能和可生物降解性能,PLLA改性电纺的PGS支架符合组织工程支架材料的基本要求。
The biodegradable poly（ glycerol sebacate） elastomer was synthesized by using 1 ∶ 1 and 1 ∶ 2two ratios of glyceryl alcohol and sebacic acid through meltcopolycondensation reaction,with the characterization analysis. Electrospinning of the blend of levorotatory polylactic acid and 1 ∶ 1 group of PGS to construct tissue engineering scaffolds. Results show that the PGS elastomer has excellent hydrophilic performance and degradation property,moreover,electrospun PGS scaffolds by PLLA blending modification accord with the basic requirement of the tissue engineering.
出处
《应用化工》
CAS
CSCD
2014年第6期975-978,共4页
Applied Chemical Industry
基金
国家自然科学基金资助项目(81160139)
关键词
聚癸二酸丙三醇酯
亲水性能
降解性能
力学性能
静电纺丝
组织工程
poly（glycerol sebacate）
hydrophilic performance
degradation property
mechanical prop-erty
electrostatic spinning
tissue engineering
